Smokeless Tobacco Products (STPs)
Enthalpy offers a range of test methods for the collection and analysis of HPHCs in smokeless tobacco products (STP) including chewing tobacco (loose leaf, plug, or twist), snus, dissolvable tobacco, and snuff (moist, dry, or in packets). This includes methods that cover a range of compounds including nicotine and the FDA’s list of HPHCs.
Smokeless Tobacco Products (STPs) are modified risk tobacco products (MRTPs) that allow nicotine delivery without combustion.
Enthalpy offers a range of test methods for the collection and analysis of select compounds in traditional STPs including chewing tobacco (loose leaf, plug, or twist), snus, dissolvable tobacco, and snuff (moist, dry, or in packets). These methods cover a range of compounds including nicotine and the FDA’s list of HPHCs. In addition, Enthalpy can assist clients with long-term stability projects with on-site and off-site storage capabilities, flavor-marker testing, dissolution / artificial saliva, and the analysis of client generated in-vitro toxicology samples.
Other related offerings:
- Tobacco-free nicotine pouches
- Oral nicotine pouches
- White pouches
- Health Canada
- FDA (USA) 2012 Abbreviated HPHC Testing
- FDA (USA) Substantial Equivalence (SE) Testing
- Analyses consistent with the Gothia Tek® standard developed by Swedish Match
Below is a list of the FDA recommended HPHC testing that Enthalpy can offer:
|HPHCs in Smokeless Tobacco|
|AM-031||TSNAs in smokeless Tobacco by LC/MS-MS: NAB,NAT,NNK,NNN|
|AM-052||Metals by ICP/MS: Arsenic, Cadmium|
|AM-072||Nicotine Content in Smokeless Tobacco by GC-FID|
|AM-125||Benzo[a]pyrene in Smokeless Tobacco by UHPLC|
|AM-238||Nicotine-N-Oxide in Tobacco by LC/MS|
|AM-240||Carbonyls in Tobacco by UPLC-MS/MS:Formaldehyde, Acetaldehyde, Crotonaldehyde|
|Smokeless Tobacco Unique Testing offering|
|MISC||Pouch Dissolution Studies|
|AM-233||Water Activity in Smokeless Tobacco|
|TOX-011||Total Yeast/Mold Count – FDA BAM: 8ed. Ch18 Total Aerobic Plate Count – AOAC 966.23|