Heated Tobacco Products
Modified Risk Tobacco Product (MRTP) Testing
Overview
Enthalpy is constantly adapting to the needs of the nicotine market. Since the onset of heated tobacco product development for tobacco harm reduction (THR), Enthalpy has been on the forefront of HNB (heat not burn) / HTP testing. Enthalpy has developed and validated a variety of HPHC methods for heated tobacco products. Below is a list of the common HPHCs Enthalpy can detect.
Testing Details
Enthalpy’s HTP product services fulfill the requirements of:
- FDA (USA) HPHC Testing
- FDA (USA) Premarket Tobacco Application (PMTA) Testing
- EU-TPD Testing
| HTP Aerosol HPC Testing |
| Method | DESCRIPTION |
| AM-099 | Triacetin by GC/MS |
| AM-216 | NO, NOx by Chemiluminescence |
| AM-245 | Semi-volatiles I by GC/MS: Acetamide, Acrylamide |
| AM-249 | Metals by ICP/MS: Arsenic, Cadmium, Chromium, Copper, Nickel, Lead |
| AM-253 | PAHs by GC/MS: Benzo[a]pyrene, Benz[a]anthracene, Dibenz[a,h]anthracene, Pyrene |
| AM-257 | Semi-volatiles II by GC/MS: Styrene, pyridine, quinoline, nitrobenzene |
| AM-262 | Carbonyls by GC/MS: Acetaldehyde, Acrolein, Acetol (Hydroxyacetone), Propionaldehyde, Acetone, Crotonaldehyde, Butyraldehyde, 2-butanone (MEK), Formaldehyde |
| AM-265 | Mercury by ICP/MS |
| AM-266 | Furan, 2-furanmethanol (Furfuryl alcohol) by GC/MS |
| AM-266 | Aromatic Amines by GCMS: o-Toluidine (2-methylaniline), 2,6-Dimethylaniline (2,”6-xylidene”), o-Anisidine (2-methoxyaniline), 1-Aminonaphthalene (1-naphthylamine), 2-Aminonaphthalene (2-naphthylamine), 3-Aminobiphenyl, 4-Aminobiphenyl, Benzidine (1,1′-biphenyl-4,4′-diamine) |
| ENT185 | Primary Constituents by GC/FID : Nicotine, Menthol, Glycerin, Propylene glycol |
| ENT185 | Carbon monoxide by CO Analyzer |
| ENT203 | Glycidol, 3-CPD by GC/MS |
| ENT208 | Volatiles by GC/MS: 1,3-Butadiene, Acrylonitrile, Benzene, Isoprene, Toluene, Propylene oxide, Ethylene oxide, Vinyl chloride |
| ENT211 | TSNAs by GC/MS/MS: NNK, NAB, NAT, NNN |
| ENT306 | Phenols by HPLC/FD: Catechol, Phenol, Hydroquinone, Resorcinol, o-Cresol, m&p-cresol |
| ENT307 | Ammonia by HPLC/IC |
| ENT335 | Hydrogen cyanide by HPLC/IC |