Company Overview

Worldwide Testing Support

Experience That Matters (20+ Years in Business)

Established in 1993 Enthalpy Analytical (Enthalpy) is a national network of accredited laboratories focused on providing our clients with responsive turnaround, best-in-class testing support, innovative science, regulatory expertise, and high-quality data. Through our collaborative process, we seek to answer the right questions so we can provide our customers the best data to support their project needs. This could be services to support regulatory and compliance requirements or providing science-based solutions for sound decision-making.

Enthalpy Analytical’s nicotine testing division was officially established in 2000. To date Enthalpy Specialty Labs is recognized as the largest nicotine testing laboratory in the United States, supporting a worldwide client base.

Enthalpy Specialty Labs operates two nicotine product testing labs in Richmond, VA and Durham, NC. Each lab is strategically located in the heart of the Southeastern Tobacco region. Our labs boast that our scientists have published expansive groundbreaking literature on a variety of nicotine research topics from aerosol test methods to synthetic nicotine. Enthalpy Specialty Labs continues to proudly serve as a leader in method development for nicotine products.

Testing Matrices:
  • ENDS
    • E-Liquid
    • Aerosol
    • E-Cigarette Devices
  • Cigarettes & Cigars
    • Cigarette & Cigar Smoke
    • Tobacco Filler
    • Roll Your Own
    • Ignition Propensity
  • Heated Tobacco Products
  • Smokeless Tobacco Products
    • Pouches (including tobacco-free nicotine / white)
    • Snus
    • Snuff
    • Chewing Tobacco
  • Hookah (Shisha or Waterpipe Tobacco)
  • Synthetic Nicotine
  • In Vitro Toxicology
    • AMES, MN (Micronucleus), Neutral Red Update (NRU)
    • Total Bacteria, Yeast, & Mold
Enthalpy Specialty Labs Specialties:
  • Product Stability & Shelf Life Studies
  • FDA Premarket Tobacco Application (PMTA) submissions
  • FDA Substantial Equivalence (SE) submissions
  • EU TPD (European Union Tobacco Products Directive)
  • Tailored solutions for research and development
  • Custom smoking and vaping regimes
  • Access to industry experts

Method Development

At Enthalpy Specialty Labs, our in vitro toxicology and analytical methodology knowledge runs deep. Our labs can analyze hundreds of harmful and potentially harmful constituents (HPHCs). Enthalpy has extensive experience with high-resolution mass spectrometry and isotope dilution quantitation. We continue to be on the cutting edge of testing. It allows us to evolve our capabilities as we learn more about this complicated industry.

Partnerships in R&D

Besides being the premier testing facility, Enthalpy is also very active in the tobacco research science community. Since its inception, Enthalpy Specialty Labs has been tapped into the pulse of the tobacco industry. Our lab is a member and guest speaker of various groups and annual conferences such as:

  • Cooperation Centre for Scientific Research Relative to Tobacco (CORESTA)
  • Tobacco Science Researchers Conference (TSRC)
  • Tobacco Merchants Association (TMA)
  • Technology Association (TA)

More importantly, Enthalpy Specialty Labs has partnered with regulatory agencies to improve research and development as it relates to public health.

Customer Service

Our comprehensive analytical services can meet our customer’s toughest challenges such as Premarket Tobacco Applications (PMTA) and Substantial Equivalency (SE) while proudly boasting a stellar customer service experience.

Subject Matter Experts & Scientists

We know our customers and we know how important your data is. Our teams of scientists, chemists, consultants, and industry experts have the experience required to understand a wide range of analytical testing needs and offer best-in-class support to a diverse group of industries.

Business Development & Project Manager

Our team of dedicated business development managers and project managers routinely work with clients to provide timely quotations, study protocols, real-time project updates, and analytical data support to help our clients through the entire testing process. We go beyond standard testing and offer advanced and specialized sciences for the tough challenges.

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